An AI tool for prioritizing candidate biomarkers from wearable sensor data
Generative AI
Generative AI
Algorithms & Theory
Skala 1.1, the updated deep-learning exchange-correlation functional from Microsoft Research, provides greater accuracy, expanded accessibility across the computational chemistry ecosystem, and a living benchmark to track computational performance. The post Broadening access to Skala creates a faster path to predictive DFT appeared first on Microsoft Research .
General Science
A path, a fence, a knot. MindTopo sets a new benchmark for testing how AI understands topological relationships and highlights new opportunities to strengthen spatial reasoning and planning. The post MindTopo reveals VLMs’ spatial reasoning abilities appeared first on Microsoft Research .
Generative AI
Health & Bioscience
Radiology AI is evolving beyond report generation. CARE-X explores a unified approach that combines flexible reasoning, calibrated predictions, and measurement-based tools for chest X-ray interpretation. The post Introducing CARE-X: Towards Clinically Useful Radiology VLMs with Auxiliary Supervision, Reward-Aligned Learning, and Tool-Augmented Measurement appeared first on Microsoft Research .
Orchard is an open-source framework for the research community to train and evaluate AI agents across task types. It reduces complexity while supporting strong performance from smaller models by enabling researchers to reuse the same infrastructure. The post Orchard: An open framework for scalable agentic AI appeared first on Microsoft Research .
General Science
Figure 1: CUDA-to-MLX optimization translation map. CUDA optimization knowledge can be translated into architecture-native MLX strategies rather than copied instruction-for-instruction. We face a new epoch in computing. Hardware is changing rapidly — not just faster GPUs, but a growing range of chips from different vendors, each with its own architecture and often tailored to specific AI workloads. Software is changing just as fast, and AI coding tools now generate in minutes what took months of effort a few years ago. With so much of computing now centered on AI, GPU kernels are a crucial component of its success. These are the low-level programs that run inside the GPU, and writing efficient ones is far from obvious — it takes years of expertise to get right. Transferring a kernel from one vendor’s hardware to another is harder still, and often means rediscovering the same optimizations from scratch. The CUDA ecosystem, for example, has accumulated decades of hard-won kernel expertise: hand-tuned implementations of attention, state space models, and other critical operations representing thousands of engineering hours. Newer hardware ecosystems (Apple Silicon, custom AI accelerat
Overview of ABBEL compared to traditional recursive summarization. Beliefs replace the full interaction history as the agent’s working context, and belief grading improves performance by supervising the contents of each belief state.. As task horizons grow, LLM contexts can’t scale forever. Self-summarization enables concise, interpretable contexts, but at a significant performance cost, especially for human assistance domains where high quality data is scarce, e.g., collaborative code generation. We address this with ABBEL : a framework that isolates and supervises the information content of summaries in the form of natural-language belief states. Motivation: the cost of recursive summarization For language models to effectively assist with increasingly complex tasks such as software development, they must be able to interact with us over hundreds or even thousands of steps. For such long tasks, it is impractical to keep the history of the entire interaction in context. The heuristic approach used so far has been summary generation, sometimes called context compaction. For example, Cursor’s latest model composer 2.5 uses compaction during training for improved performance ( Cassan
... government of the people, by the people, for the people ... — Abraham Lincoln, Gettysburg Address (1863) The cost of AI is dropping rapidly. GPT-4-class capabilities cost roughly $30 per million tokens in early 2023; today the same runs under $1 , and some providers are pushing costs below $0.10 . Across benchmarks, inference prices have fallen between 9x and 900x per year , with a median decline near 50x. Even frontier models are getting dramatically cheaper each generation, with open-source models following closely behind. And crucially, even if “Nobel-Prize-winning genius-level” intelligence isn’t here yet, the intelligence that suffices for the vast majority of knowledge work is here today, and getting cheaper by the month. At this rate, we are soon entering the era of virtually free intelligence —the kind that is more than enough for everyday knowledge work. Disclosure: This post is a perspective led by Aditya G. Parameswaran —an Associate Professor of EECS and co-director of the EPIC Data Lab at UC Berkeley—together with his collaborators. It is part landscape survey and part perspective, and several of the research directions discussed below (including agentic speculatio
Congratulations to the Berkeley Artificial Intelligence Research (BAIR) Lab class of 2026! This year, BAIR celebrates another remarkable group of Ph.D. graduates whose curiosity, creativity, and perseverance have pushed the frontiers of artificial intelligence and machine learning. Their work spans the breadth of modern AI — robotics and embodied intelligence, large language models and reasoning, computer vision, generative modeling, AI safety, human-AI interaction, AI for science and healthcare, and much more. Along the way, they have published influential research, built systems with real-world impact, mentored their peers, and shaped the BAIR community for the better. Now they are headed everywhere ideas travel: to faculty and postdoctoral positions, to industry research labs, and to startups of their own founding — and several are still exploring what comes next and would love to hear from you. Please join us in celebrating the achievements of these wonderful graduates. We are proud of everything they have accomplished at Berkeley, and we can’t wait to see what they do next! Thank you to our friends at the Stanford AI Lab for this idea! Baifeng Shi Email: baifeng_shi@berkeley.e
Overview of adaptive parallel reasoning. What if a reasoning model could decide for itself when to decompose and parallelize independent subtasks, how many concurrent threads to spawn, and how to coordinate them based on the problem at hand? We provide a detailed analysis of recent progress in the field of parallel reasoning, especially Adaptive Parallel Reasoning. Disclosure: this post is part landscape survey, part perspective on adaptive parallel reasoning. One of the authors (Tony Lian) co-led ThreadWeaver ( Lian et al., 2025 ), one of the methods discussed below. The authors aim to present each approach on its own terms. Motivation Recent progress in LLM reasoning capabilities has been largely driven by inference-time scaling, in addition to data and parameter scaling ( OpenAI et al., 2024 ; DeepSeek-AI et al., 2025 ). Models that explicitly output reasoning tokens (through intermediate steps, backtracking, and exploration) now dominate math, coding, and agentic benchmarks. These behaviors allow models to explore alternative hypotheses, correct earlier mistakes, and synthesize conclusions rather than committing to a single solution ( Wen et al., 2025 ). The problem is that seq
GRASP is a new gradient-based planner for learned dynamics (a “world model”) that makes long-horizon planning practical by (1) lifting the trajectory into virtual states so optimization is parallel across time, (2) adding stochasticity directly to the state iterates for exploration, and (3) reshaping gradients so actions get clean signals while we avoid brittle “state-input” gradients through high-dimensional vision models. Large, learned world models are becoming increasingly capable. They can predict long sequences of future observations in high-dimensional visual spaces and generalize across tasks in ways that were difficult to imagine a few years ago. As these models scale, they start to look less like task-specific predictors and more like general-purpose simulators. But having a powerful predictive model is not the same as being able to use it effectively for control/learning/planning. In practice, long-horizon planning with modern world models remains fragile: optimization becomes ill-conditioned, non-greedy structure creates bad local minima, and high-dimensional latent spaces introduce subtle failure modes. In this blog post, I describe the problems that motivated this pro
Understanding the behavior of complex machine learning systems, particularly Large Language Models (LLMs), is a critical challenge in modern artificial intelligence. Interpretability research aims to make the decision-making process more transparent to model builders and impacted humans, a step toward safer and more trustworthy AI. To gain a comprehensive understanding, we can analyze these systems through different lenses: feature attribution , which isolates the specific input features driving a prediction ( Lundberg & Lee, 2017 ; Ribeiro et al., 2022 ); data attribution , which links model behaviors to influential training examples ( Koh & Liang, 2017 ; Ilyas et al., 2022 ); and mechanistic interpretability , which dissects the functions of internal components ( Conmy et al., 2023 ; Sharkey et al., 2025 ). Across these perspectives, the same fundamental hurdle persists: complexity at scale . Model behavior is rarely the result of isolated components; rather, it emerges from complex dependencies and patterns. To achieve state-of-the-art performance, models synthesize complex feature relationships, find shared patterns from diverse training examples, and process information throug
An encoder (optical system) maps objects to noiseless images, which noise corrupts into measurements. Our information estimator uses only these noisy measurements and a noise model to quantify how well measurements distinguish objects. Many imaging systems produce measurements that humans never see or cannot interpret directly. Your smartphone processes raw sensor data through algorithms before producing the final photo. MRI scanners collect frequency-space measurements that require reconstruction before doctors can view them. Self-driving cars process camera and LiDAR data directly with neural networks. What matters in these systems is not how measurements look, but how much useful information they contain. AI can extract this information even when it is encoded in ways that humans cannot interpret. And yet we rarely evaluate information content directly. Traditional metrics like resolution and signal-to-noise ratio assess individual aspects of quality separately, making it difficult to compare systems that trade off between these factors. The common alternative, training neural networks to reconstruct or classify images, conflates the quality of the imaging hardware with the qual
In this post, I’ll introduce a reinforcement learning (RL) algorithm based on an “alternative” paradigm: divide and conquer . Unlike traditional methods, this algorithm is not based on temporal difference (TD) learning (which has scalability challenges ), and scales well to long-horizon tasks. We can do Reinforcement Learning (RL) based on divide and conquer, instead of temporal difference (TD) learning. Problem setting: off-policy RL Our problem setting is off-policy RL . Let’s briefly review what this means. There are two classes of algorithms in RL: on-policy RL and off-policy RL. On-policy RL means we can only use fresh data collected by the current policy. In other words, we have to throw away old data each time we update the policy. Algorithms like PPO and GRPO (and policy gradient methods in general) belong to this category. Off-policy RL means we don’t have this restriction: we can use any kind of data, including old experience, human demonstrations, Internet data, and so on. So off-policy RL is more general and flexible than on-policy RL (and of course harder!). Q-learning is the most well-known off-policy RL algorithm. In domains where data collection is expensive ( e.g.
What exactly does word2vec learn, and how? Answering this question amounts to understanding representation learning in a minimal yet interesting language modeling task. Despite the fact that word2vec is a well-known precursor to modern language models, for many years, researchers lacked a quantitative and predictive theory describing its learning process. In our new paper , we finally provide such a theory. We prove that there are realistic, practical regimes in which the learning problem reduces to unweighted least-squares matrix factorization . We solve the gradient flow dynamics in closed form; the final learned representations are simply given by PCA. Learning dynamics of word2vec . When trained from small initialization, word2vec learns in discrete, sequential steps. Left: rank-incrementing learning steps in the weight matrix, each decreasing the loss. Right: three time slices of the latent embedding space showing how embedding vectors expand into subspaces of increasing dimension at each learning step, continuing until model capacity is saturated. Before elaborating on this result, let’s motivate the problem. word2vec is a well-known algorithm for learning dense vector repres